SPP2453 “Integration of mitochondria into the cellular proteostasis network”
The Priority Program SPP2453, consisting of 33 research groups from different German research institutions, is funded by the German Research Foundation (DFG) since September 2024. A particular feature of the Priority Program is the nationwide collaboration between its participating researchers. The research consortium aims to investigate how mitochondrial biogenesis and function are embedded into the cellular proteostasis network. For this, joint forces from two different disciplines are used: Experts in mitochondrial protein biogenesis and experts in cellular proteostasis will combine highly innovative techniques to obtain central insights into these fundamental cell biological processes. The findings will contribute to a better understanding of molecular mechanisms underlying aging and the development of neurodegenerative diseases. Read more...
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AUGUST 2026: Virtual Issue 26 in Protein Science: Integration of Mitochondria into the Cellular Proteostasis Network
New Virtual Issue in "Protein Science"
The new Virtual Issue (Vol. 26, 2026) of the journal Protein Science focuses on “Integration of mitochondria into the cellular proteostasis network”, corresponding to our priority program SPP2453. In this special issue of Protein Science, the current understanding of mitochondrial protein biogenesis regarding protein targeting, protein import pathways, assembly processes and quality control mechanisms is covered by experts in the field.
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Principal Investigators
38
Young Scientists
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Scientific Projects
